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In enzymology, a deoxycytidylate 5-hydroxymethyltransferase () is an enzyme that catalyzes the chemical reaction :5,10-methylenetetrahydrofolate + H2O + deoxycytidylate tetrahydrofolate + 5-hydroxymethyldeoxycytidylate The 3 substrates of this enzyme are 5,10-methylenetetrahydrofolate, H2O, and deoxycytidylate, whereas its two products are tetrahydrofolate and 5-hydroxymethyldeoxycytidylate. This enzyme belongs to the family of transferases that transfer one-carbon groups, specifically the hydroxymethyl-, formyl- and related transferases. The systematic name of this enzyme class is 5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase. Other names in common use include dCMP hydroxymethylase, d-cytidine 5'-monophosphate hydroxymethylase, deoxyCMP hydroxymethylase, deoxycytidylate hydroxymethylase, and deoxycytidylic hydroxymethylase. This enzyme participates in pyrimidine metabolism and one carbon pool by folate. ==Structural studies== As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes , , and . 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Deoxycytidylate 5-hydroxymethyltransferase」の詳細全文を読む スポンサード リンク
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